“Elucidating phenoconversion through molecular phenotyping”

I have been working on several research topics including obesity, infectious diseases, cancers and rare diseases over the last 7 years. To extract meaningful biochemical data out of specimens, multi-omics platforms including genomics, transcriptomics, proteomics and metabolomics, are employed to visualize the dynamically altering phenotypes in response to diseases and treatments.

Postgraduate student supervision

Main supervision

MSc:

Phuc N. M. Ho – Black soldier fly-derived anti-microbial peptides against skin diseases (2019 – Present)

Rujikorn Treeriya – Fecal microbiota composition and function in cholangiocarcinoma patients (2018 – present)

Co-supervision

PhD:

Leakkhaing Taing – Effects of bioactive compounds derived from rice germs on longevity (2019 – present)

Kanokrat Thaiwatcharamas, MD – Microbiome and metabolome of patients with Hirschsprung’s disease (2019 – present)

Thitiwan Jumpa – Effects of salinity stress on metabolic and physiological adaptation of Oryza sativa L. (2018 – present)

Pattralak Songserm – Antioxidant and anti-cancer properties of bioactive compounds derived from callus of Rhinacanthus nasutus (2018 – 2021)

Sureerat Padthisong – Post-operative recurrence biomarker discovery in cholangiocarcinoma (2017 – 2021)

Yingpinyapat Kittirat – Effects of chemotherapy on cancer-associated fibroblast in cholangiocarcinoma (2017 – present)

Kanokwan Nahok – Alkaline property of monosodium glutamate and its medical implications (2019 – present)

MSc:

Chainarong Bunma – Interactions and metabolomics profiling of Burkholderia
pseudomallei biofilm phenotype during encounter with Acanthamoeba sp. (2019 – present)

Sirinya Sitthirak – Association of tissue microbiome-metabolome and chemotherapeutic response patterns of cholangiocarcinoma patients (2019 – present)

Kwuanjira Chaleekan – Development of cholangiocarcinoma patients-derived organoid (2019 – present)

Pimpawadee Phukhum – Development of cholangiocarcinoma spheroid for drug testing model (2019 – present)

Saikhim Sringan – Metabolic profiling of patients-derived cancer-associated fibroblasts (2018 – present)

Tinnapat Seaban – Pharmacometabolomics of gemcitabine-responsive cholangiocarcinoma cells (2018 – 2021)

Thanaporn Kulthawatsiri – Effects of niclosamide on metabolic alteration of cholangiocarcinoma cells (2017 – 2019)

Pattama Prommajun – Metabolic profiling of praziquantel-mediated prevention of Opisthorchis viverrini-induced cholangiocyte transformation in the hamster model of cholangiocarcinoma (2017 – 2019)